SoHo is bounded by Houston Street on the northern side, Canal Street on the south, Crosby Street on the east, and Sixth Avenue to the west, according to The Encyclopedia of New York City. SoHo Alliance, Manhattan Community Board and the Greenwich Village Society for Historic Preservation give the western boundary of SoHo north of Broome Street as West Broadway, as does the AIA Guide to New York City.

In the 2000s, real estate agents began giving an adjacent neighborhood below West Houston Street various appellations, with no general agreement on whether it should be called West SoHo, Hudson Square or the South Village. The AIA Guide calls that neighborhood "An intersection of brick and glass, searching for an identity," and refers to the western section of it as "The Glass Box District.